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Description

Mitochondrial images were deconvoluted with Huygens (Scientific Volume Imaging) by using the Classic Maximum Likelihood Estimation algorithm (CMLE)

Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation

Nicotinamide analogs such as 6-methylaminonicotinamide form one class of NNMT inhibitors that work by mimicking the natural substrate, NAM, and competing for the enzymes active site 197